Evaluation of Wound Healing Potential of Aerial Parts of Cardiospermum Halicacabum Linn

Cardiospermum halicacabum (Linn) popularly called as balloon wine belongs to Sapindaceae family. Phytochemical constituents such as flavones, apigenin, triterpenoidal glycosides fatty acids and volatile ester have been reported in C. halicacabum. In the present study the aerial parts of C. halicacabum were studied for wound healing activity by incorporating extract in simple ointment base B.P. in concentration of 2% (w/w) and 4% (w/w) and studied in three types of model in rats viz. excision, incision and burn wound model. The statistical data indicated that the wound with ointment containing 4% w/w alcoholic extract exhibited significant (P < 0.001) wound contracting ability and period of epithelization. Significant tensile strength was observed with both the ointment formulations 2% w/w and 4% w/w. The experimental data demonstrated that C. halicacabum displayed remarkable wound healing activity.